ProCE Banner Activity


A Focus on Special Populations: Optimizing Direct Oral Anticoagulant Use for Stroke Prevention in Atrial Fibrillation

Interactive Video Lecture

There are misconceptions about use of direct oral anticoagulants (DOACs) to prevent stroke in special populations of patients with atrial fibrillation (AF). Recent evidence shows that with appropriate selection, DOACs can be safely used to prevent stroke in patients with AF who are elderly, have chronic kidney disease (CKD), end-stage renal disease (ESRD), or who have obesity. In this 1-hour webcast, 2 cardiology experts review the evidence and latest guidance for treatment of these populations with DOACs. Cases demonstrate assessment of bleeding risk and key decision points for managing each type of scenario.

Physician Assistants: maximum of 1.00 hours of AAPA Category 1 CME credits Registered Nurses: 1.00 Nursing contact hours, includes 1.00 hour of pharmacology credit

Released: February 01, 2022

Expiration: January 31, 2023

No longer available for credit.



Kimberly A. Berggren

Kimberly A. Berggren, DMSc, PA-C

Electrophysiology Physician Assistant
Okaloosa Heart and Vascular Center
Fort Walton Beach, Florida

Laura Ross

Laura Ross, PA-C, CLS, AACC, DipACLM

Physician Assistant
Department of Cardiology
Park Nicollet Heart and Vascular Center Methodist Hospital
St. Louis Park, Minnesota

Christian T. Ruff

Christian T. Ruff, MD, MPH

Associate Professor of Medicine
Harvard Medical School
Director of General Cardiology
Brigham and Women's Hospital
Boston, Massachusetts


This activity is supported by an educational grant from Janssen Pharmaceuticals, Inc., administered by Janssen Scientific Affairs, LLC

Target Audience

NPs and PAs in Cardiology

Learning Objectives

Upon completion of this activity, participants should be able to:
  • Summarize the available evidence related to bleeding risk of older adults receiving a DOAC versus warfarin for stroke prevention in AF

  • Discuss the risks and benefits of anticoagulation therapy for stroke prevention in patients with severe CKD or ESRD

  • Describe the most recent efficacy and safety data for the use of DOACs in patients with AF and severe obesity


Ms Berggren has no relevant financial relationships to disclose.

Ms Ross has no relevant financial relationships to disclose.

Dr Ruff: consulting fees: Bayer, Bristol-Myers Squibb, Janssen, Pfizer; consulting fees/contracted research (paid to institution): Anthos, Boehringer Ingelheim, Daiichi Sankyo; contracted research (paid to institution): AstraZeneca.

None of the members of the Planning Committee or PCE staff have any relevant relationships to disclose.

Instructions for Credit

Participants wishing to earn CE/CME credit must:

  1. View the content in its entirety
  2. Relate the content material to the learning objectives
  3. Complete the evaluation form

The estimated time to complete this activity is 1.00 hour.

Release date: February 1, 2022
Expiration date: January 31, 2023


Interactive video lecture


The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange or any educational supporter.



Joint Accreditation Statement

Joint AccreditationIn support of improving patient care, Practicing Clinicians Exchange is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

ANCC Credit Designation

NP course advisor: Darcy H. Thiesen, CNP, MSN, Park Nicollet Heart and Vascular Center, St Louis Park, Minnesota

Nursing contact hours: 1.00, which includes 1.00 hour of pharmacology credit

AAPA Credit Designation

Joint AccreditationPracticing Clinicians Exchange has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credit. PAs should only claim credit commensurate with the extent of their participation.

IPCE Credit Designation
IPCEThis activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.

Additional Information

Program Medium

This program has been made available online.