The proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors alirocumab and evolocumab dramatically reduce low-density lipoprotein cholesterol levels—by about 60%—and outcomes studies show that they have the potential to improve morbidity and mortality from atherosclerotic cardiovascular disease (ASCVD). Usually used in combination with statins, these self-administered injectable agents (given once or twice monthly) are already changing standards of care for dyslipidemia. National and international medical associations recognize their value and have included them in their treatment algorithms, which should facilitate approval by insurance programs. In this CE/CME activity, a prominent lipidologist provides expert guidance for using these new agents.
Interactive clinical review and case study
After completing this activity, participants should be better able to:
- Devise treatment strategies based on current guidelines and clinical trial evidence for patients with dyslipidemia, including patients not reaching goals on maximally tolerated statin therapy
- Apply guideline updates to facilitate selection of the dyslipidemia treatment that will most effectively reduce ASCVD risk
- Develop a patient-centered approach to improve adherence and access to lipid-lowering therapy
NPs and PAs
There are no prerequisites to participate in this activity.
Continuing Nursing Education Provider Unit, Boston University School of Medicine is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.
This educational activity has been provided by Continuing Nursing Education Provider Unit, Boston University School of Medicine and jointly provided by Practicing Clinicians Exchange.
Contact hours: 1.0, which are eligible for 1.0 pharmacology credits.
Course director: Jason Worcester, MD, Boston University School of Medicine
CNE course advisor: Claire Murphy, MSN, NP-C, Boston University School of Medicine
This activity has been reviewed by the AAPA Review Panel and is compliant with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credits. Approval is valid for one year from 10/31/2018. PAs should only claim credit commensurate with the extent of their participation.
This program was cosupported by educational grants from Amgen; Astellas; Boehringer Ingelheim Pharmaceuticals, Inc. and Lilly USA, LLC; Genentech; Gilead Sciences, Inc.; Neurocrine Biosciences and Teva Pharmaceuticals; Sanofi US; Shire; and Sunovion Pharmaceuticals, Inc.
This activity is supported by an educational grant from Amgen.
The opinions or views expressed in this continuing education activity are those of the faculty and do not necessarily reflect the opinions or recommendations of the American Academy of Physician Assistants, Boston University School of Medicine, Continuing Education Alliance, Practicing Clinicians Exchange, or any educational supporter.
THIS CONTINUING MEDICAL EDUCATION PROGRAM IS INTENDED SOLELY FOR EDUCATIONAL PURPOSES FOR QUALIFIED HEALTHCARE PROFESSIONALS. IN NO EVENT SHALL BOSTON UNIVERSITY BE LIABLE FOR ANY DECISION MADE OR ACTION TAKEN IN RELIANCE ON THE INFORMATION CONTAINED IN THE PROGRAM. IN NO EVENT SHOULD THE INFORMATION CONTAINED IN THE PROGRAM BE USED AS A SUBSTITUTE FOR PROFESSIONAL CARE. NO PHYSICIAN-PATIENT RELATIONSHIP IS BEING ESTABLISHED.
Boston University School of Medicine asks all individuals involved in the development and presentation of Continuing Medical Education (CME) activities to disclose all relevant relationships with commercial interests. This information is disclosed to CME activity participants. Boston University School of Medicine has procedures to resolve any apparent conflicts of interest. In addition, faculty members are asked to disclose when any discussion of unapproved use of pharmaceuticals and devices is being discussed.
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the US Food and Drug Administration.
Dr Jacoby: consultant/education: Quest Diagnostics.
The Planning Committee for this activity included Claire Murphy, MSN, NP-C, Carmela A. Townsend, DNP, MS/MBA, RN, Jody Walker, MS, Julie L. White, MS, and Jason Worcester, MD, of Boston University School of Medicine; Mark Christiansen, PhD, PA-C, of the University of the Pacific; and Ruth Cohen, Warren Beckman, and Margaret Inman of Practicing Clinicians Exchange. None of the aforementioned members of the Planning Committee have any relevant relationships to disclose.
Participants wishing to earn CE/CME credit must:
- Read the content
- Relate the content material to the learning objectives
- Complete the post-test and evaluation form online
Successful completion of the post-test is required to earn CE/CME credit. Successful completion is defined as a cumulative score of at least 70%.
The estimated time to complete each activity is 1 hour.
Release date: October 31, 2018
Expiration date: October 30, 2019
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