Acute lymphoblastic leukemia (ALL) is a serious hematologic malignancy associated with substantial morbidity and mortality. While 89% to 90% of adults with ALL achieve a complete response, half of them will relapse. The use of pediatric-inspired regimens, minimal residual disease (MRD)-directed therapy, biologics, and CAR T-cell therapy may yield important benefits in adolescent/young adult patients and adults with ALL. Patient education regarding potential adverse events, expectations, and treatment adherence is critical for optimizing outcomes. In this case-based activity, participants will evaluate the diagnosis and risk stratification of two patients with ALL, select induction regimens—including novel agents—and apply strategies to mitigate toxicities.
Case studies with interactive benchmarking
After completing this activity, participants should be better able to:
- Describe clinical factors, subtypes, and cytogenetic factors that impact diagnosis and classification of ALL
- Identify evidence for novel and emerging agents for ALL
- Apply strategies to mitigate toxicities associated with novel therapies
Oncology NPs, PAs, and nurses
Joint Accreditation Statement
In support of improving patient care, Practicing Clinicians Exchange is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
ANCC Credit Designation
Nursing contact hours: 1.00, which includes 1.00 hour of pharmacology credit
AAPA Credit Designation
Practicing Clinicians Exchange has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credit. Approval is valid until December 20, 2021. PAs should only claim credit commensurate with the extent of their participation.
PA course advisor: Corinne Williams, PA-C, Northwestern University Feinberg School of Medicine, Chicago, Illinois
IPCE Credit Designation
This activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.
This activity is supported by an educational grant from Servier Pharmaceuticals.
The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange or any educational supporter.
All faculty and planners participating in continuing education activities sponsored by Practicing Clinicians Exchange are required to disclose to the audience any relevant support or substantial relationships with providers of commercial products and/or devices discussed in this activity and/or with any commercial supporters of the activity. In addition, all faculty are required to openly disclose any off-label, experimental, or investigational use of drugs or devices discussed in this activity. The faculty and planning committee have been advised that this activity must be free from commercial bias, and based upon all the available scientifically rigorous data from research that conforms to accepted standards of experimental design, data collection, and analysis.
Dr Leak Bryant has no relevant financial relationships to disclose.
Ms Williams: speakers bureau: AstraZeneca.
None of the members of the planning committee or PCE staff have any relevant relationships to disclose, except Ms Williams as noted above.
Participants wishing to earn CE/CME credit must:
- Read the content in its entirety
- Relate the content material to the learning objectives
- Complete the post-test and evaluation form
Successful completion of the post-test is required to earn CE/CME credit. Successful completion is defined as a cumulative score of at least 70%.
The estimated time to complete this activity is 1.00 hour.
Release date: December 21, 2020
Expiration date: December 20, 2021
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