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Chronic Constipation: Going Beyond Over-the-Counter Therapies

PCE On Demand Live Presentation

In this webcast, expert faculty provides steps for the diagnosis of chronic idiopathic constipation and how best to establish individualized treatment regimens based on the current recommendations and efficacy and safety evidence and that better address patient dissatisfaction with OTC approaches.

Physician Assistants/Physician Associates: 1.00 AAPA Category 1 CME credit

Nurse Practitioners: 1.00 Nursing contact hours, includes 1.00 hour of pharmacotherapy credit

Released: January 06, 2023

Expiration: January 05, 2024

No longer available for credit.



Darren M. Brenner

Darren M. Brenner, MD, FACG, AGAF, RFF

Professor of Medicine and Surgery
Irene D. Pritzker Foundation Research Scholar
Division of Gastroenterology
Department of Internal Medicine
Northwestern University Feinberg School of Medicine
Chicago, Illinois

Daniel Zalinov

Daniel Zalinov, PA-C

Internal Medicine
Atrium Health
Charlotte, North Carolina

Provided by

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This activity is supported by educational grants from:


Ironwood Pharmaceuticals

Target Audience

NPs and PAs in primary care

Learning Objectives

After completing this activity, participants should be better able to

  • Summarize signs and symptoms important to the differential diagnosis of CIC 

  • Plan nonpharmacologic approaches for the management of CIC in patients

  • Individualize the pharmacologic treatment of CIC based on current recommendations and efficacy and safety evidence


All faculty and planners participating in continuing education activities sponsored by Partners for Advancing Clinical Education (PACE) are required to disclose all financial relationships with ineligible companies. All relevant conflicts of interest are thoroughly vetted and mitigated according to PCE policy. In addition, all faculty are required to openly disclose any off-label, experimental, or investigational use of drugs or devices discussed in this activity. The faculty and Planning Committee have been advised that this activity must be free from commercial bias and based upon all available scientifically rigorous data from research that conforms to accepted standards of experimental design, data collection, and analysis.

Darren M. Brenner, MD, FACG, AGAF, RFF: consultant/advisor/speaker: AbbVie, Alfasigma, Alnylam, Ardelyx, Arena, Bayer, Gemelli, Ironwood, QOL Medical, Redhill, Salix, Takeda, Vibrant.

Daniel Zalinov, PA-C has no relevant financial relationships to disclose.

The planners and content peer reviewers from Partners for Advancing Clinical Education and Practicing Clinicians Exchange do not have any relevant financial relationships to disclose.

Instructions for Credit

Learners wishing to earn CE/CME credit must: 

  1. View the content in its entirety
  2. Relate the content material to the learning objectives 
  3. Complete evaluation form 

The estimated time to complete this activity is 1.00 hour.


This program has been made available online.


The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange, Partners for Advancing Clinical Education, or any educational supporter.


Joint Accreditation Statement
Joint Accreditation In support of improving patient care, Partners for Advancing Clinical Education (PACE) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


ANCC Credit Designation
Nursing contact hours: 1.00, which includes 1.00 hours of pharmacology credit


AAPA Credit Designation
Joint AccreditationPartners for Advancing Clinical Education (PACE) has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credit. Approval is valid until January 05, 2024. PAs should only claim credit commensurate with the extent of their participation.


IPCE Credit Designation
IPCEThis activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.