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Improving Response to Antidepressant Therapy: What Are the Options?

PCE On Demand Live Presentation

Major depressive disorder (MDD) affects approximately 16 million adults in the United States and has a significant impact on work, home, and social activities. MDD is highly recurrent, and many patients do not recover after initial treatment and subsequently experience chronic depression, impaired psychosocial functioning, and poor overall general health. Tune in to this webcast to hear expert faculty recommendations on achieving and maintaining remission of MDD through the use of validated monitoring tools.

Physician Assistants/Physician Associates: 1.00 AAPA Category 1 CME credit

Nurse Practitioners: 1.00 Nursing contact hours, includes 1.00 hour of pharmacotherapy credit

Released: January 04, 2023

Expiration: January 03, 2024

No longer available for credit.



Denise Vanacore

Denise Vanacore, PhD, FNP-BC, PMHNP-BC

Professor of Nursing
Graduate Program Director
Gwynedd Mercy University
Gwynedd Valley, Pennsylvania

Provided by

Provided by Partners for Advancing Clinical Education (PACE)

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This activity is supported by an educational grant from:

Takeda Pharmaceuticals U.S.A., Inc.

Target Audience

Primary Care NPs and PAs

Learning Objectives

After completing this activity, participants should be better able to:

  • Use validated tools to monitor patient response to MDD therapy

  • Identify treatment strategies to address inadequate response to MDD therapy

  • Formulate strategies to address patient adherence to and engagement in the treatment of MDD


All faculty and planners participating in continuing education activities sponsored by Partners for Advancing Clinical Education (PACE) are required to disclose all financial relationships with ineligible companies. All relevant conflicts of interest are thoroughly vetted and mitigated according to PCE policy. In addition, all faculty are required to openly disclose any off-label, experimental, or investigational use of drugs or devices discussed in this activity. The faculty and Planning Committee have been advised that this activity must be free from commercial bias and based upon all available scientifically rigorous data from research that conforms to accepted standards of experimental design, data collection, and analysis.

Denise Vanacore, PhD, FNP-BC, PMHNP-BC: speaker: AbbVie.

The planners and content peer reviewers from Partners for Advancing Clinical Education and Practicing Clinicians Exchange do not have any relevant financial relationships to disclose.

Instructions for Credit

Learners wishing to earn CE/CME credit must: 

  1. View the content in its entirety
  2. Relate the content material to the learning objectives 
  3. Complete evaluation form 

The estimated time to complete this activity is 1.00 hour.


This program has been made available online


The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange, Partners for Advancing Clinical Education, or any educational supporter.


Joint Accreditation Statement
Joint AccreditationIn support of improving patient care, Partners for Advancing Clinical Education (PACE) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.


ANCC Credit Designation
Nursing contact hours: 1.00, which includes 1.00 hour of pharmacology credit


AAPA Credit Designation
Joint AccreditationPartners for Advancing Clinical Education (PACE) has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credit. Approval is valid until January 03, 2024. PAs should only claim credit commensurate with the extent of their participation.


PA course advisor: Stephanie Jalaba, MMS, PA-C, Michigan State University, East Lansing, Michigan


IPCE Credit Designation
IPCEThis activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.