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Influenza Updates: A Focus on High-Risk Patients


Influenza poses a unique challenge to healthcare providers with variations in annual strains, seasonality, and the need to encourage annual vaccination to vaccine-hesitant patients. In addition, it can be difficult to discern flu from other respiratory illnesses—including COVID-19. Various testing platforms, antivirals, and vaccines are available to help providers diagnose, manage, and prevent influenza and provide optimal care; this activity provides clinical pearls for use of these components in clinical practice, with a focus on high-risk patients.

Physician Assistants: maximum of 1.00 hours of AAPA Category 1 CME credits Registered Nurses: 1.00 Nursing contact hours, includes 1.00 hour of pharmacology credit

Released: March 31, 2022

Expiration: March 30, 2023

No longer available for credit.



Paul G. Auwaerter

Paul G. Auwaerter, MD, MBA

Sherrilyn and Ken Fisher Professor of Medicine
Clinical Director
Division of Infectious Diseases
Johns Hopkins University School of Medicine
Baltimore, Maryland


This program is cosupported by educational grants from Alcon Vision, LLC; Biohaven Pharmaceuticals; Genentech, a member of the Roche Group; Gilead Sciences, Inc.; and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC.

This activity is supported by an educational grant from Genentech, a member of the Roche Group.

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Genentech, a member of the Roche Group

Target Audience

Physicians, NPs, and PAs

Learning Objectives

Upon completion of this activity, participants should be able to:
  • Plan strategies for flu treatment in adult patients at high risk for complications

  • Summarize the available and emerging options for management of influenza in high-risk patients

  • Individualize flu treatment for pediatric patients based on recent trial data and current recommendations


All faculty and planners participating in continuing education activities sponsored by Practicing Clinicians Exchange (PCE) are required to disclose all financial relationships with ineligible companies. All relevant conflicts of interest are thoroughly vetted and mitigated according to PCE policy. In addition, all faculty are required to openly disclose any off-label, experimental, or investigational use of drugs or devices discussed in this activity. The faculty and Planning Committee have been advised that this activity must be free from commercial bias and based upon all available scientifically rigorous data from research that conforms to accepted standards of experimental design, data collection, and analysis.

Dr Auwaerter: consulting fees: Adaptive Biotherapeutics, EMD Serono, Humanigen, Verily; consulting fees/contracted research: Pfizer; ownership interest: Johnson & Johnson.

Dr Herman: fees for non-CME/CE services: Novo Nordisk.

None of the members of the Planning Committee or PCE staff have any relevant relationships to disclose, except Dr Herman as noted above.

Instructions for Credit

Participants wishing to earn CE/CME credit must:

  1. Review the content in its entirety
  2. Relate the content material to the learning objectives
  3. Complete the post-test and evaluation form

Successful completion of the post-test is required to earn CE/CME credit. Successful completion is defined as a cumulative score of at least 67%.

The estimated time to complete this activity is 1.00 hour.

Release date: March 31, 2022
Expiration date: March 30, 2023


Interactive case study with video clips


The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange or any educational supporter.



Joint Accreditation Statement

Joint AccreditationIn support of improving patient care, Practicing Clinicians Exchange is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

AMA Credit Designation

Practicing Clinicians Exchange designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

ANCC Credit Designation

NP course advisor: Mary Knudtson, DNSc, NP, FAAN, University of California, Irvine, Irvine, California. Nursing contact hours: 1.00, which includes 1.00 hour of pharmacology credit

AAPA Credit Designation

Joint AccreditationPracticing Clinicians Exchange has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credit. Approval is valid until March 30, 2023. PAs should only claim credit commensurate with the extent of their participation.

PA course advisor: Lawrence Herman, DMSc, MPA, PA-C, University of Lynchburg, Lynchburg, Virginia

IPCE Credit Designation
IPCEThis activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.

Additional Information

Program Medium

This program has been made available online.