Increased understanding of the genetic and molecular alterations that influence the development of renal cell carcinoma (RCC) has led to the development of new therapies that have revolutionized the treatment of advanced RCC. The standard of care for first-line therapy has shifted to immunotherapy-based combination regimens, as immune checkpoint inhibitors have enriched the treatment landscape in this setting, as well as in the second-line setting. The biggest challenges in treatment are selecting the optimal agent from the growing list of drugs and effectively managing toxicities. This activity addresses risk factors for RCC, the importance of histology in prognosis and treatment, and management of the disease in the context of the evolving treatment landscape.
eNewsletters with interactive benchmarking
After completing this activity, participants should be better able to:
- Formulate treatment strategies for advanced RCC based on current evidence and patient/disease factors
- Identify potential immune-related adverse events and their onset during and after therapy
- Implement strategies to recognize and appropriately manage side effects associated with tyrosine kinase inhibitors for advanced RCC
Oncology NPs, PAs, and nurses
Joint Accreditation Statement
In support of improving patient care, Practicing Clinicians Exchange is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
ANCC Credit Designation
Course director: Lee Schwartzberg, MD, FACP, West Cancer Center, Germantown, Tennessee
CNE course advisor: Beth Sandy, MSN, CRNP, Abramson Cancer Center, Philadelphia, Pennsylvania
Nursing contact hours: 1.00, which includes 1.00 hour of pharmacology credit
AAPA Credit Designation
Practicing Clinicians Exchange has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credit. Approval is valid until August 14, 2021. PAs should only claim credit commensurate with the extent of their participation.
PA course advisor: Corinne Williams, PA-C, Northwestern University Feinberg School of Medicine, Chicago, Illinois
IPCE Credit Designation
This activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.
This program was developed from a series of programs cosupported by educational grants from Astellas; Astellas and Pfizer; Celgene Corporation; Exelixis; GlaxoSmithKline; Karyopharm Therapeutics; Merck & Co., Inc.; Pharmacyclics LLC, an AbbVie Company; Sanofi Genzyme; Seattle Genetics; and Verastem Oncology.
This activity is supported by educational grants from Merck and Exelixis.
The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange or any educational supporter.
All faculty and planners participating in continuing education activities sponsored by Practicing Clinicians Exchange are required to disclose to the audience any relevant support or substantial relationships with providers of commercial products and/or devices discussed in this activity and/or with any commercial supporters of the activity. In addition, all faculty are required to openly disclose any off-label, experimental, or investigational use of drugs or devices discussed in this activity. The faculty and planning committee have been advised that this activity must be free from commercial bias, and based upon all the available scientifically rigorous data from research that conforms to accepted standards of experimental design, data collection, and analysis.
Dr Gao has no relevant financial relationships to disclose.
Ms Sandy: speakers bureau: AstraZeneca, Merck, Takeda.
Dr Schwartzberg: consultant: Amgen, AstraZeneca, Bristol-Myers Squibb, Genentech/Roche, Pfizer, Spectrum.
Ms Williams: speakers bureau: AstraZeneca.
None of the members of the PCE staff have any relevant relationships to disclose.
Participants wishing to earn CE/CME credit must:
- Read the content in its entirety
- Relate the content material to the learning objectives
- Complete the post-test and evaluation form online
Successful completion of the post-test is required to earn CE/CME credit. Successful completion is defined as a cumulative score of at least 70%.
Release date: August 15, 2020
Expiration date: August 14, 2021
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