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Transforming the Care of Patients With Non-Small-Cell Lung Cancer: Optimizing Immune Checkpoint Inhibitor Therapy

Patient Simulation

The advent of immune checkpoint inhibitors (ICIs) has been a significant advance in the management of patients with non-small-cell lung cancer (NSCLC). This interactive virtual patient simulation activity with 3 different patient case scenarios will allow learners to explore evidence-based recommendations to individualize the management of patients with NSCLC using ICI therapy, including opportunities to identify and manage immune related adverse events.

For a quick review of the key evidence before starting these patient simulations, please see the associated expert commentary, downloadable slideset and downloadable resource. For a more focused review, please see the associated on-demand webcast.

Physician Assistants: maximum of 1.50 hours of AAPA Category 1 CME credits Registered Nurses: 1.50 Nursing contact hours, includes 1.50 hour of pharmacology credit

Released: August 17, 2022

Expiration: August 16, 2023

No longer available for credit.



Elizabeth Krueger

Elizabeth Krueger, NP

Nurse Practitioner
Massachusetts General Hospital Cancer Center
Boston, Massachusetts


This activity is supported by educational grants from Bristol Myers Squibb; Genentech, a member of the Roche Group; Merck Sharp & Dohme Corp.; and Regeneron Pharmaceuticals, Inc and Sanofi.

Provided by

ProCE Banner


Bristol Myers Squibb

Genentech, a member of the Roche Group

Merck Sharp & Dohme Corp.

Regeneron Pharmaceuticals, Inc


Target Audience

Oncology NPs, PAs, and nurses

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Identify currently approved ICIs and the role of biomarker testing in their use in advanced NSCLC

  • Describe recommended, evidence-based strategies to individualize treatment with ICIs for patients with advanced NSCLC

  • Implement effective strategies for identification and management of immune-related adverse events in patients treated with ICIs


All faculty and planners participating in continuing education activities sponsored by Practicing Clinicians Exchange (PCE) are required to disclose all financial relationships with ineligible companies. All relevant conflicts of interest are thoroughly vetted and mitigated according to PCE policy. In addition, all faculty are required to openly disclose any off-label, experimental, or investigational use of drugs or devices discussed in this activity. The faculty and Planning Committee have been advised that this activity must be free from commercial bias and based upon all available scientifically rigorous data from research that conforms to accepted standards of experimental design, data collection, and analysis.

Elizabeth Krueger, NP, has no relevant financial relationships to disclose.

None of the members of the Planning Committee or PCE staff have any relevant financial relationships to disclose.

Instructions for Credit

Participants wishing to earn CE/CME credit must:

  1. Complete the content in its entirety
  2. Relate the content material to the learning objectives
  3. Complete post-test and evaluation form

Successful completion of the post-test is required to earn CE/CME credit. Successful completion is defined as a cumulative score of at least 67%.

The estimated time to complete this activity is 1.50 hours.

Release date: August 17, 2022
Expiration date: August 16, 2023


Patient Simulation

In this virtual simulation platform program, you will meet 3 patients with non-small-cell lung cancer. The program will have you proceed through your patient’s history, overview of the current situation, and physical exam. It enables you to obtain additional information by ordering laboratory values, imaging, and to make referrals. As the patient scenario warrants, add your recommendations for diagnosis, treatments, and follow-up. End your patient visit and schedule a follow-up. At each end-of-visit, you will see your progress in achieving the predetermined goals for the case. Each case will test your ability to diagnose and prescribe evidence-based recommendations to improve care.


The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange or any educational supporter.



Joint Accreditation Statement

Joint AccreditationIn support of improving patient care, Practicing Clinicians Exchange is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

ANCC Credit Designation

Nursing contact hours: 1.50, which includes 1.50 hours of pharmacology credit

AAPA Credit Designation

Joint AccreditationPracticing Clinicians Exchange has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.50 AAPA Category 1 CME credits. Approval is valid until August 16, 2023. PAs should only claim credit commensurate with the extent of their participation.

PA course advisor: Jessica Garner, DMSc, PA-C, University of the Pacific, Sacramento, California

IPCE Credit Designation
IPCEThis activity was planned by and for the healthcare team, and learners will receive 1.50 Interprofessional Continuing Education (IPCE) credits for learning and change.

Additional Information

Program Medium

This program has been made available online.