Breaking the Cycle in OSA Webcast : Pre-test

1.

A 36-yr-old man with obesity presents with complaints of daytime sleepiness, difficulty concentrating at work, and loud snoring at night. His BMI is 43 kg/m². A sleep study confirms the diagnosis of obstructive sleep apnea (OSA). How comfortable are you with educating this patient about the pathophysiologic connection between obesity and OSA?

A. Not comfortable
B. Somewhat not comfortable
C. Neutral
D. Somewhat comfortable
E. Comfortable

2.

How confident are you with initiating and managing pharmacotherapy for the management of obesity in your patients with OSA?

A. Not confident
B. Somewhat not confident
C. Neutral
D. Somewhat confident
E. Confident

3.

A 49-yr-old woman with BMI 41 kg/m² and AHI 33/hr on CPAP presents to your clinic. She has prediabetes, controlled hypertension, and no history of cardiovascular disease. She is highly motivated to lose weight to improve her OSA. Based on the SURMOUNT trial, which of the following statements best describes the goal of tirzepatide in this patient’s care?

A. It can improve OSA but may cause blood pressure to increase, limiting its use in patients with hypertension
B. It is only effective for treatment of OSA in patients who also have T2D
C. It can decrease her AHI primarily through weight loss and offers additional cardiometabolic benefits
D. It will decrease her BMI by up to 20% and increase her AHI by up to 15%

4.

A 55-yr-old man (BMI 37 kg/m²) with moderate OSA managed on CPAP presents for follow-up. His blood pressure is well controlled with medications. He has been adherent to CPAP but remains fatigued and is frustrated with minimal weight loss. He asks what additional steps could help with his OSA and improve his energy level. Which of the following strategies best addresses long-term obesity management as part of his OSA care?

A. Continue CPAP and add lifestyle interventions to improve weight loss
B. Use a short course of phentermine to accelerate initial weight loss, then taper after 12 wk
C. Focus on CPAP adherence; weight loss medications should be reserved until OSA improves
D. Initiate an incretin-based therapy to promote sustained weight loss and improve OSA severity

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Breaking the Cycle: Prioritizing Weight Loss to Improve OSA Management

Jaime Almandoz, MD, MBA, MRCPI, FTOS, DABOM

Radhika S. Breaden, MD, MPH, DABMS, DABOM

H-C Carol Huang, BHB, MBChB, FRACP

Babak Mokhlesi, MD, MSc

Amanda J. Piper, PhD

Rafael Sepulveda, MD, DABMS, DABOM

Audrey Wells, MD

Pretest

Please answer the questions below.

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