Treat to Target in CD

CE / CME

Interactive Case Challenge 1: Treat-to-Target in Crohn’s Disease 

Physician Assistants/Physician Associates: 0.50 AAPA Category 1 CME credit

Nurse Practitioners/Nurses: 0.50 Nursing contact hour

Physicians: maximum of 0.50 AMA PRA Category 1 Credit

ABIM MOC: maximum of 0.50 Medical Knowledge MOC point

Released: March 17, 2025

Expiration: March 16, 2026

Pretest

Progress
1 2 3
Course Completed
Please answer the questions below.
1.

A 28-year-old biologic-naive woman with moderate to severe ileal Crohn’s disease (CD) (Simple Endoscopic Score for Crohn's Disease [SES-CD] of ≥7) reports ongoing symptoms despite initial therapy with prednisone 30 mg/day. Colonoscopy shows active terminal ileal ulcerations with an SES-CD of 9, and biomarkers reveal elevated C-reactive protein (CRP) at 7 mg/L (upper limit of normal: 5 mg/L) and fecal calprotectin 550 μg/g.

What is most appropriate next step in her management?