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Targeting Huntington’s Disease: Current and Emerging Options

Text Module

Huntington’s disease (HD) is an inherited, progressive, neurodegenerative disorder that results in cognitive impairment, psychiatric/behavioral changes, and impaired motor function, including characteristic chorea. Although trials investigating disease-modifying therapies are in progress, there is currently no cure for HD, and the average life expectancy is 15-20 years after diagnosis. Disease management focuses on alleviating symptoms, maximizing function, and optimizing quality of life. In this activity, Victor W. Sung, MD, addresses key topics in the management of adult-onset HD, including early recognition and diagnosis, current and emerging therapies, advances in chorea treatments, and the role of primary care clinicians in multidisciplinary management.

Physician Assistants: maximum of 1.00 hours of AAPA Category 1 CME credits Registered Nurses: 1.00 Nursing contact hours, includes 1.00 hour of pharmacology credit

Released: December 30, 2021

Expiration: December 29, 2022

No longer available for credit.



Victor W. Sung

Victor W. Sung, MD

Department of Neurology
Division of Movement Disorders
Clinic Director
Huntington's Disease Clinic/HDSA Center of Excellence
University of Alabama at Birmingham
Birmingham, Alabama


This activity is supported by an educational grant from Teva Pharmaceuticals.

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Target Audience

NPs and PAs

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Describe the potential motor, cognitive, and psychiatric signs and symptoms across the spectrum of HD

  • Screen patients for early signs and symptoms of HD

  • Summarize current and emerging therapeutic options for management of chorea in HD


All faculty and planners participating in continuing education activities sponsored by Practicing Clinicians Exchange (PCE) are required to disclose to the audience all financial relationships with ineligible companies. All relevant conflicts of interest are thoroughly vetted and mitigated according to PCE policy. In addition, all faculty are required to openly disclose any off-label, experimental, or investigational use of drugs or devices discussed in this activity. The faculty and Planning Committee have been advised that this activity must be free from commercial bias and based upon all available scientifically rigorous data from research that conforms to accepted standards of experimental design, data collection, and analysis.

Dr Gibson: contracted research/consulting fees/fees for non-CE/CME services: Teva Pharmaceuticals.

Dr Sung: consulting fees: Teva Pharmaceuticals.

None of the members of the Planning Committee or PCE staff have any relevant relationships to disclose, except Dr Gibson as noted above.

Instructions for Credit

Participants wishing to earn CE/CME credit must:

  1. Review the content in its entirety
  2. Relate the content material to the learning objectives
  3. Complete the post-test and evaluation form

Successful completion of the post-test is required to earn CE/CME credit. Successful completion is defined as a cumulative score of at least 67%.

The estimated time to complete this activity is 1.00 hour.

Release date: December 30, 2021
Expiration date: December 29, 2022


eNewsletter with interactive benchmarking and audio commentary


The opinions or views expressed in this CE/CME activity do not necessarily reflect the opinions or recommendations of Practicing Clinicians Exchange or any educational supporter.



Joint Accreditation Statement

Joint AccreditationIn support of improving patient care, Practicing Clinicians Exchange is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

ANCC Credit Designation

NP Course Advisor: Jessie Gibson, PhD, RN, AGPCNP-BC, University of Virginia School of Nursing, Charlottesville, Virginia

Nursing contact hours: 1.00, which includes 1.00 hour of pharmacology credit

AAPA Credit Designation

Joint AccreditationPracticing Clinicians Exchange has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1.00 AAPA Category 1 CME credit. Approval is valid until December 29, 2022. PAs should only claim credit commensurate with the extent of their participation.

PA Course Advisor: Mark Christiansen, PhD, PA-C, University of the Pacific, Sacramento, California

IPCE Credit Designation
IPCEThis activity was planned by and for the healthcare team, and learners will receive 1.00 Interprofessional Continuing Education (IPCE) credit for learning and change.

Additional Information

Program Medium

This program has been made available online.