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Practical Guidance for the Care of Patients With HR+/HER2- MBC With Comorbidities

Video

Listen to a nurse practitioner and a physician assistant discuss the role of advanced practice providers in providing optimal patient-centric care for patients with HR-positive/HER2-negative MBC and preexisting comorbid conditions, including the efficacy and approaches for the management of the adverse events associated with the standard-of-care agents.

Nurse Practitioners/Nurses: 1.00 Nursing contact hour

Physician Assistants/Physician Associates: 1.00 AAPA Category 1 CME credit

Released: May 12, 2025

Expiration: November 11, 2025

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Provided by Clinical Care Options, LLC., in partnership with Practicing Clinicians Exchange (PCE) and ProCE, LLC.

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Supporters

Supported by an educational grant from Pfizer Inc.

Pfizer Inc.

Partners

Practicing Clinicians Exchange, LLC

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ProCE, LLC

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Target Audience

This activity is intended for oncology nurses and nurse practitioners, physician associates, and other healthcare professionals involved in caring for patients with mBC.

Program Learning Goal

This activity aims to improve learners' knowledge, competence, and performance in improving the comprehensive care of patients with HR+/HER2- mBC and existing comorbidities. 

Learning Objectives

Upon completion of this activity, participants should be able to:

  • Describe common comorbidities and related factors in patients with HR+/HER2- MBC, including cardiovascular disease, polypharmacy, and poor performance status

  • Implement effective multidisciplinary team processes to mitigate and monitor potential drug–drug interactions in patients with comorbid conditions 

  • Plan communication strategies, utilizing shared decision-making to optimize patient–physician trust and understand patient goals when selecting MBC treatment 

Disclosure

Clinical Care Options, LLC (CCO) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose all financial conflicts of interest (COI) they may have with ineligible companies. All relevant COI are thoroughly vetted and mitigated according to CCO policy. CCO is committed to providing its learners with high-quality CME/CE activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of an ineligible company.

The faculty reported the following relevant financial relationships or relationships to products or devices they have with ineligible companies related to the content of this educational activity:

Primary Author

La-Urshalar B. Brock, FNP-BC, CNM, PhD Candidate: consultant/advisor/speaker: AstraZeneca.

Elizabeth Diaz, PA-C, has no relevant financial relationships to disclose.

The planners and content peer reviewers from Clinical Care Options, LLC, Practicing Clinicians Exchange (PCE), and ProCE, LLC do not have any relevant financial relationships to disclose.

Instructions for Credit

Participation in this self-study activity should be completed in approximately 1 hour. To successfully complete this activity and receive credit, participants must follow these steps during the period from May 12, 2025, through November 11, 2025:

  1. Login or Sign Up for an account by clicking at the top of this page.
  2. Read the target audience, learning objectives, and faculty disclosures.
  3. View and study the content in its entirety.
  4. Submit answers to the posttest questions and evaluation questions online.

You must receive a test score of at least 65 and respond to all evaluation questions to receive a certificate. After submitting the evaluation, you may access your online certificate by selecting the certificate link on the confirmation page. Records of all CME/CE activities completed can be found on the "My Certificates" page. There are no costs/fees for this activity.

Format

This program has been made available online.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Accreditation

Joint Accreditation Statement

In support of improving patient care, Clinical Care Options, LLC (CCO) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Nursing Continuing Professional Development

The maximum number of hours awarded for this Nursing Continuing Professional Development activity is 1 contact hour.

Physician Associate Continuing Medical Education

Clinical Care Options, LLC has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for 1 AAPA Category 1 CME credit. Approval is valid until November 11, 2025. PAs should only claim credit commensurate with the extent of their participation.