The Exchange

Commentary and Observations from
the Medical Front Lines

Kristine Kucera, PA-C, MPAS, DHS

Kristine Kucera, PA-C, MPAS, DHS

  • Associate Professor
  • UT Southwestern Medical School
  • Dallas, Texas
  • Physician Assistant
  • North Texas Dermatology
  • Richardson, Texas
Biologics in Psoriasis

Biologics in Psoriasis

The current understanding of the pathogenesis of psoriasis has led to the development of many immune-mediating biologic medications that specifically target overactive inflammatory cytokines. Biologics are different from traditional systemic drugs that impact the entire immune system in that they block the actions of specific types of immune cells and proteins that play a major role psoriatic disease.

There are several biologics approved by the US Food and Drug Administration that a... Continue Reading

Filed under: Dermatology

Understanding the Pathophysiology of Psoriasis

Understanding the Pathophysiology of Psoriasis

Psoriasis is a chronic, inflammatory, recurrent, immune-mediated disease that affects more than 8 million people in the United States. It can occur at any ag... Continue Reading

Filed under: Dermatology

Phytophotodermatitis: Skin Rash With a Twist

Phytophotodermatitis: Skin Rash With a Twist

Phytophotodermatitis, also known as the "margarita rash," is a commonly seen condition in the spring and summer months or any time a patient has had exposure... Continue Reading

Filed under: Dermatology

Sign of the Times: Facial Mask Irritation

Sign of the Times: Facial Mask Irritation

Masks trap moisture, sweat, oil, and dirt close to our skin. The resulting blemishes often include acne: small, inflamed bumps and irritation. Those irritati... Continue Reading

Filed under: Dermatology

Spironolactone Use in Adult Female Acne

Spironolactone Use in Adult Female Acne

Acne is an inflammatory skin condition that is usually seen in adolescence. However, it is becoming more common past the teenage years, often affecting those... Continue Reading

Filed under: Dermatology

Skin Manifestations of COVID-19

Skin Manifestations of COVID-19

By now it is well known that COVID-19 is an illness caused by the SARS-CoV-2 virus that may lead to serious respiratory disease. The most common sy... Continue Reading

Filed under: Dermatology, Infectious Diseases

Using Topical Steroids Safely and Effectively

Using Topical Steroids Safely and Effectively

Since their introduction in early 1950s, topical corticosteroids (TCS) have become the drugs most commonly prescribed by dermatologists for outpatients and a... Continue Reading

Filed under: Dermatology

Determining the Cause of Hair Loss

Determining the Cause of Hair Loss

Hair loss, also known as alopecia, is one of the of most common disorders that dermatology practitioners diagnose and treat. With so many potential causes, i... Continue Reading

Filed under: Dermatology

Hidradenitis suppurativa

Hidradenitis suppurativa

Hidradenitis suppurativa (HS) is a chronic, debilitating, inflammatory disease of the hair follicle that usually develops after puberty. It presents with pai... Continue Reading

Filed under: Dermatology

Sun Protection

Sun Protection

In the late 1970s, the promotion of sun protection was almost nonexistent, even though Swiss researcher, Franz Greiter, had developed the concept of sun prot... Continue Reading

Filed under: Dermatology

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