Managing mCRC

CE / CME

Opportunities and Challenges in Management of Metastatic Colorectal Cancer

Physician Assistants/Physician Associates: 1.00 AAPA Category 1 CME credit

Nurse Practitioners: 1.00 Nursing contact hours, includes 1.00 hour of pharmacotherapy credit

Released: May 02, 2023

Expiration: May 01, 2024

Robert Lentz
Robert Lentz, MD

Activity

Progress
1
Course Completed

Which of the following is the significance of dMMR/MSI-H in selecting therapy for mCRC?

Which of the following is a characteristic of immune-related adverse events associated with anti-PD-1 ICI therapy?

Which of these is the recommended second-line option for patients with BRAFV600E-mutated mCRC?

Sarah is receiving pembrolizumab to treat unresectable mCRC. She develops grade 1 immune-related colitis after 2 cycles, with 3-4 bouts of diarrhea daily. What would be your recommendation for management?

Max, 75, has mCRC with progression after 1L chemotherapy + bevacizumab. His molecular profile is MSS, RAS WT, BRAF WT, and HER2+ (ERBB+ on NGS). Which of these is a recommended option for his next therapy?

How often do you currently ensure that patients with mCRC are undergoing recommended molecular testing?

How often do you currently recommend 1L chemotherapy + EGFR inhibitor for patients with newly diagnosed, left-sided RAS/BRAF wild-type mCRC?

How often do you currently monitor renal and hepatic function in patients with mCRC prior to each infusion of pembrolizumab?

Sarah, 46, has been diagnosed with unresectable mCRC. Her molecular profile is dMMR/MSI-H, BRAFV600E+, RAS WT, and HER2 and NTRK negative. Which of these is the recommended initial treatment option for her?

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